Publications

Ogata S, Hashizume K, Hayase Y, Kanno Y, Hori K, Balan S, Yoshikawa T, Takahashi H, Taya S, Hoshino M.
Potential involvement of DSCAML1 mutations in neurodevelopmental disorders.
Genes Cells. 2021 Jan 27. doi: 10.1111/gtc.12831. online ahead

Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, Ihara N, Yamakawa K, Taya S, Hoshino M.
Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.
Acta Neuropathol Commun. 2020 Nov 30;8(1):206. doi: 10.1186/s40478-020-01082-6.

Hiraga K, Inoue YU, Asami J, Hotta M, Morimoto Y, Tatsumoto S, Hoshino M, Go Y, Inoue T.
Redundant type II cadherins define neuroepithelial cell states for cytoarchitectonic robustness.
Commun Biol. 2020 Oct 15;3(1):574. doi: 10.1038/s42003-020-01297-2

Yamashiro K, Hori K, Esther L, Aoki R, Shimaoka K, Arimura N, Egusa SF, Sakamoto A, Abe M, Sakimura K, Watanabe T, Uesaka N, Kano M, Hoshino M.
AUTS2 governs cerebellar development purkinje cell maturation, motor function and social communication
iScience.2020 Dec 18. doi：10.1016/j.isci.2020.101820

Yamashita M, Owa T, Shiraishi R, Adachi T, Ichijo K, Taya S, Miyashita S, Hoshino M.
The role of SCFSkp2 and SCFβ-TrCP1/2 in the cerebellar granule cell precursors.
Genes Cells. 2020 Oct 6. doi: 10.1111/gtc.12813. Online ahead of print.

Kutscher LM, Okonechnikov K, Batora NV, Clark J, Silva PBG, Vouri M, van Rijn S, Sieber L, Statz B, Gearhart MD, Shiraishi R, Mack N, Orr BA, Korshunov A, Gudenas BL, Smith KS, Mercier AL, Ayrault O, Hoshino M, Kool M, von Hoff K, Graf N, Fleischhack G, Bardwell VJ, Pfister SM, Northcott PA, Kawauchi D.
Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation.
Genes Dev. 2020 Sep 1;34(17-18):1161-1176. doi: 10.1101/gad.337584.120. Epub 2020 Aug 20.

Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, Kaibuchi K, Hoshino M.
DSCAM regulates delamination of neurons in the developing midbrain
Science Advances Pub Date:2020 Sep 2;6(36):eaba1693. doi: 10.1126/sciadv.aba1693.PMID: 32917586 DOI: 10.1126/sciadv.aba1693

Hori K, Yamashiro K, Nagai T, Shan W, Egusa SF, Shimaoka K, Kuniishi H, Sekiguchi M, Go Y, Tatsumoto S, Yamada M, Shiraishi R, Kanno K, Miyashita S, Sakamoto A, Abe M, Sakimura K, Sone M, Sohya K, Kunugi H, Wada K, Yamada M, Yamada K, Hoshino M.
AUTS2 Regulation of Synapses for Proper Synaptic Inputs and Social Communication.
iScience. 2020 Jun 26;23(6):101183. doi: 10.1016/j.isci.2020.101183. Epub 2020 May 18.PMID: 32498016 Free PMC article.

Pajtler KW, Wei Y, Okonechnikov K, Silva PBG, Vouri M, Zhang L, Brabetz S, Sieber L, Gulley M, Mauermann M, Wedig T, Mack N, Imamura Kawasawa Y, Sharma T, Zuckermann M, Andreiuolo F, Holland E, Maass K, Körkel-Qu H, Liu HK, Sahm F, Capper D, Bunt J, Richards LJ, Jones DTW, Korshunov A, Chavez L, Lichter P, Hoshino M, Pfister SM, Kool M, Li W, Kawauchi D.
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.
Nat Commun. 2019 Sep 2;10(1):3914. doi: 10.1038/s41467-019-11884-5.PMID: 31477715 Free PMC article.

Shiraishi RD, Miyashita S, Yamashita M, Adachi T, Shimoda MM, Owa T, Hoshino M.
Expression of transcription factors and signaling molecules in the cerebellar granule cell development.
Gene Expr Patterns. 2019 Dec;34:119068. doi: 10.1016/j.gep.2019.119068. Epub 2019 Aug 20.PMID: 31437514

Takizawa H, Hara Y, Mizobe Y, Ohno T, Suzuki S, Inoue K, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Hoshino M, Komaki H, Takeda S, Aoki Y.
Modelling Duchenne muscular dystrophy in MYOD1-converted urine-derived cells treated with 3-deazaneplanocin A hydrochloride.
Sci Rep. 2019 Mar 7;9(1):3807. doi: 10.1038/s41598-019-40421-z.PMID: 30846748 Free PMC article.

Arimura N, Dewa KI, Okada M, Yanagawa Y, Taya SI, Hoshino M.
Comprehensive and cell-type-based characterization of the dorsal midbrain during development.
Genes Cells. 2019 Jan;24(1):41-59. doi: 10.1111/gtc.12656. Epub 2018 Dec 5.

Ambrozkiewicz MC, Schwark M, Kishimoto-Suga M, Borisova E, Hori K, Salazar-Lazaro A, Rusanova A, Altas B, Piepkorn L, Bessa P, Schaub T, Zhang X, Rabe T, Ripamonti S, Rosario M, Akiyama H, Jahn O, Kobayashi T, Hoshino M, Tarabykin V, Kawabe H.
Polarity Acquisition in Cortical Neurons Is Driven by Synergistic Action of Sox9-Regulated Wwp1 and Wwp2 E3 Ubiquitin Ligases and Intronic miR-140.
Neuron100:1097-1115 e1015. doi.org/10.1016/j.neuron.2018.10.008

Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Marutani M, Shibuya A, Nabeshima Y, Yanagisawa M, Funato H and Hoshino M.
Forebrain Ptf1a is required for sexual differentiation of the brain.
Cell Rep., 2018 July 3; 24(1):79-94. doi:10.1016/j.celrep.2018.06.010

Inoue YU, Morimoto Y, Hoshino M, Inoue T:
Generation of Pax6-IRES-EGFP knock-in mouse via the cloning-free CRISPR/Cas9 system to reliably visualize neurodevelopmental dynamics.
Neurosci Res, 2018 Jan 31. pii: S0168-0102(17)30718-6. doi: 10.1016/j.neures.2018.01.007. [Epub ahead of print]

Owa T, Taya S, Miyashita S, Yamashita M, Adachi T, Yamada K, Yokoyama M, Aida S, Nishioka T, Inoue YU, Goitsuka R, Nakamura T, Inoue T, Kaibuchi K, Hoshino M:
Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation.
J Neurosci, 2018 Jan 31;38(5):1277-1294. doi: 10.1523/JNEUROSCI.1545-17.2017. Epub 2018 Jan 9.

Russo D, Della Ragione F, Rizzo R, Sugiyama E, Scalabrì F, Hori K, Capasso S, Sticco L, Fioriniello S, De Gregorio R, Granata I, Guarracino MR, Maglione V, Johannes L, Bellenchi GC, Hoshino M, Setou M, D’Esposito M, Luini A, D’Angelo G:
Glycosphingolipid metabolic reprogramming drives neural differentiation.
EMBO J, 2017 Dec 27. pii: e97674. doi: 10.15252/embj.201797674. [Epub ahead of print]

Miyashita S, Adachi T, Yamashita M, Sota T, Hoshino M:
Dynamics of the cell division orientation of granule cell precursors during cerebellar development.
Mech Dev, 2017 Oct;147:1-7. doi: 10.1016/j.mod.2017.06.002. Epub 2017 Jun 17.

Hori K, Hoshino M:
Neuronal Migration and AUTS2 Syndrome.
Brain Sci, 2017 May 14;7(5). pii: E54. doi: 10.3390/brainsci7050054. Review.

Hanai S, Sukigara S, Dai H, Owa T, Horike SI, Otsuki T, Saito T, Nakagawa E, Ikegaya N, Kaido T, Sato N, Takahashi A, Sugai K, Saito Y, Sasaki M, Hoshino M, Goto YI, Koizumi S, Itoh M:
Pathologic Active mTOR Mutation in Brain Malformation with Intractable Epilepsy Leads to Cell-Autonomous Migration Delay.
Am J Pathol, 2017 May;187(5):1177-1185. doi: 10.1016/j.ajpath.2017.01.015.

Hashimoto R, Hori K, Owa T, Miyashita S, Dewa K, Masuyama N, Sakai K, Hayase Y, Seto Y, Inoue YU, Inoue T, Ichinohe N, Kawaguchi Y, Akiyama H, Koizumi S, Hoshino M:
Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9.
Mech Dev, May;140:25-40. doi: 10.1016/j.mod.2016.02.004. Epub 2016 Mar 3.

Leto K, Arancillo M, Becker EB, Buffo A, Chiang C, Ding B, Dobyns WB, Dusart I, Haldipur P, Hatten ME, Hoshino M, Joyner AL, Kano M, Kilpatrick DL, Koibuchi N, Marino S, Martinez S, Millen KJ, Millner TO, Miyata T, Parmigiani E, Schilling K, Sekerková G, Sillitoe RV, Sotelo C, Uesaka N, Wefers A, Wingate RJ, Hawke:
Consensus paper: cerebellar development.
Cerebellum, 2016 Dec;15(6):789-828. Review.

Egusa SF, Inoue YU, Asami J, Terakawa YW, Hoshino M, Inoue T:
Classiic cadherin expressions balance postnatal neuronal positioning and dendrite dynamics to elaborate the specific cytoarchitecture of the mouse cortical area.
Neurosci Res, 2016 Apr;105:49-64. doi: 10.1016/j.neures.2015.09.006. Epub 2015 Oct 9.

Hori K, Nagai T, Shan W, Sakamoto A, Abe M, Yamazaki M, Sakimura K, Yamada K, Hoshino M:
Heterozygous disruption of Autism susceptibility candidate 2 causes impaired emotional control and cognitive memory.
PLoS One, 10, e0145979, 2015

Yamaguchi M, Watanabe Y, Ohtani T, Uezumi A, Mikami N, Nakamura M, Sato T, Ikawa M, Hoshino M, Tsuchida K, Miyagoe-Suzuki Y, Tsujikawa K, Takeda S, Yamamoto H, Fukuda S:
Calcitonin receptor signalling inhibits muscle stem cells from escaping the quiescent state and the niche.
Cell Reports, 13, 302-314 2015

Watanabe T, Kakeno M, Matsui T, Sugiyama I, Arimura N, Matsuzawa K, Shirahige A, Ishidate F, Nishioka T, Taya S, Hoshino M, Kaibuchi K:
TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation.
J Cell Biol. 2015

Wright MC, Reed-Geaghan EG, Bolock AM, Fujiyama T, Hoshino M, Maricich SM:
Unipotent Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.
J Cell Biol, 208, 367-377, 2015

Ito H, Shiwaku H, Yoshida C, Homma H, Luo H, Chen X, Musante L, Fischer U, Frints SGM, Romano C, Ikeuchi Y, Shimamura T, Imoto S, Miyano S, Kawauchi T, Hoshino M, Sudol M, Arumughan A, Wanker EE, Rich T, Schwartz C, Matsuzaki F, Bonni A, Kalscheuer VM, Okazawa H:
In utero gene therapy rescues microcephaly caused by Pqbp1-hypofunction in neural stem progenitor cells.
Molecular Psychiatry, 20, 459-471, 2015.

Ruffault P-L, D’Autreaux F, Hayes JA, Nomaksteinsky M, Autran S, Fujiyama T, Hoshino M, Hagglund M, Kiehn O, Brunet J-F, Fortin G, Goridis C:
The retrotrapezoid nucleus neurons expressing Atoh1 and Phox2b are essential for the respiratory response to CO2.
eLife, 10.7554, 2015

De Luca A, Parmigiani E, Tosatto G, Martire S, Hoshino M, Buffo A, Leto K, Rossi F:
Exogenous Sonic Hedgehog modulates the pool of GABAergic interneurons during cerebellar development.
Cerebellum, 14, 72-85, 2015.

Seto Y, Nakatani T, Masuyama N, Taya S, Kumai M, Minaki Y, Hamaguchi A, Inoue YU, Inoue T, Miyashita S, Fujiyama T, Yamada M, Chapman H, Campbell KJ, Magnuson MA, Wright CV, Kawaguchi Y, Ikenaka K, Takebayashi H, Ishiwata S, Ono Y, Hoshino M:
Temporal identity transition from Purkinje cell progenitors to GABAergic interneuron progenitors in the cerebellum.
Nature Communications, 5, 3337, 2014

Hori K, Nagai T, Shan W, Sakamoto A, Taya S, Hashimoto R, Hayashi T, Abe M, Yamazaki M, Nakao K, Nishioka T, Sakimura K, Yamada K, Kaibuchi K, Hoshino M:
Cytoskeletal regulation of AUTS2 in neuronal migration and neuritogenesis.
Cell Reports, 9, 2166-2179, 2014

Yamada M, Seto Y, Taya S, Owa T, Inoue YU, Inoue T, Kawaguchi Y, Nabeshima Y, Hoshino M:
Specification of spatial identities of cerebellar neuronal progenitors by Ptf1a and Atoh1 for proper production of GABAergic and glutamatergic neurons.
J. Neurosci, 34, 4786-4800, 2014

Worzfeld T, Swiercz JM, Senturk A, Genz B, Korostylev A, Deng S, Xia J, Hoshino M, Epstein JA, Chang AM, Vollmar B, Acker-Palmer A, Kuner R, Offermanns S:
Genetic dissection of plexin signalling in vivo.
Proc Natl Acad Sci USA , 111, 2194-2199, 2014

Seto Y, Ishiwata S, Hoshino M:
Characterization of Olig2 expression during cerebellar development.
Gene Expression Patterns, 15, 1-7, 2014

Nishimura YV, Shikanai M, Hoshino M, Ohshima T, Nabeshima Y, Mizutani K, Nagata K, Nakajima K, Kawauchi T:
Cdk5 and its substrates, DCX and p27-kip1, regulate cytoplasmic dilation formation and nuclear elongation in migrating neurons.
Development, 141, 3540-3550, 2014.

Chonko KT, Jahan I, Stone J, Wright MC, Fujiyama T, Hoshino M, Fritzsch B, Maricich SM:
Atoh1 directs hair cell differentiation and survival in the late embryonic mouse inner ear.
Dev Biol. 381, 401-410, 2013

Terakawa YW, Inoue YU, Asami J, Hoshino M, Inoue T:
A sharp Cadherin-6 gene expression boundary in the developing mouse cortical plate demarcates the future functional areal border.
Cerebral Cortex. 23, 2293-2308, 2013

Esposito G, Yoshida S, Ohnishi R, Tsuneoka Y, Rostagno Mdel C, Yokota S, Okabe S, Kamiya K, Hoshino M, Shimizu M, Venuti P, Kikusui T, Kato T, Kuroda KO:
Infant calming responses during maternal carrying in humans and mice.
Current Biology, 23, 739-745, 2013

Bjerknes M, Khandanpour C, Moroy T, Fujiyama T, Hoshino M, Klisch TJ, Ding Q, Gan L, Wang J, Martin MG, Chen H:
Origin of the brush cell lineage in the mouse intestinal epithelium.
Dev Biol, 362, 194-218, 2012

Morinaka A, Yamada M, Itofusa R, Funato Y, Yoshimura Y, Nakamura F, Yoshimura T, Kaibuchi K, Goshima Y, Hoshino M, Kamiguchi H, Miki H:
Thioredoxin mediates oxidation-dependent phosphorylation of CRMP2 and growth cone collapse.
Sicence Signaling, 4 (170), ra26, 2011

Goto A, Hoshino M, Matsuda M, Nakamura T:
Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cells.
Mol BIol Cell, 22, 1780-1790, 2011

Komine O, Nagaoka M, HIraoka Y, Hoshino M, Kawaguchi Y, Pear WS, Tanaka K:
RBP-J promotes the maturation of neuronal progenitors.
Dev Biol, 354, 44-54, 2011

Matsumoto A, Susaki E, Onoyama I, Nakayama K, Hoshino M, Nakayama KI:
Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice.
Mol Cell Biol, 31, 4176-4192, 2011

Kawauchi T, Sekine K, Shikanai M, Chihama K, Tomita K, Nakajima K, Nabeshima Y, Hoshino M:
Rab GTPases-dependent endocytic pathways regulate neuronal migration and maturation through N-Cadherin trafficking.
Neuron, 67, 588-602, 2010

Nishida K, Hoshino M, Kawaguchi Y, Murakami F:
Ptf1a directly controls expression of immunoglobulin superfamily molecules Nephrin and Neph3 in the developing central nervous system.
J. Biol. Chem. 285, 373-380, 2010

Nishimura YV, Sekine K, Chihama K, Nakajima K, *Hoshino M, Nabeshima Y, *Kawauchi T:
Dissecting the factors involved in the locomotion mode of neuronal migration in the developing cerebral cortex.
J. Biol. Chem. 285, 5878-5887, 2010

Iritani S, Sekiguchi H, Habuchi C, Hikita T, Taya S, Kaibuchi K, Ozaki N:
Immunohistochemical study of vesicle monoamine transporter 2 in the hippocampal region of genetic animal model of schizophrenia.
Synapse, 64, 948-953, 2010

Miyahara K, Kato Y, Koga H, Lane GJ, Inoue T, Akazawa C, Yamataka, A:
Abnormal enteric innervation identified without histopathologic staining in aganglionic colorectum from a mouse model of Hirschsprung’s disease.
J Pediatr Surg. 45:2403-2407, 2010.

Shibata S, Yasuda A, Renault-Mihara F, Suyama S, Katoh H, Inoue T, Inoue YU, Nagoshi N, Sato M, Nakamura M, Akazawa C, Okano H:
Sox10-Venus mice: a new tool for real-time labeling of neural crest lineage cells and oligodendrocytes.
Mol. Brain 3:31, 2010

Fujiyama T, Yamada M, Terao M, Terashima T, Hioki H, Inoue YU, Inoue T, Masuyama N, Obata K, Yanagawa Y, Kawaguchi Y, Nabeshima Y, Hoshino M:
Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1.
Development, 136, 2049-2058, 2009

Causeret F, Terao M, Jacobs T, Nishimura YV, Yanagawa Y, Obata K, Hoshino M, Nikolic M:
The p21-activated kinase is required for neuronal migration in the cerebral cortex.
Cerebral Cortex, 19, 861-875, 2009

Inoue YU, Asami J, Inoue T:
Genetic labeling of mouse rhombomeres by Cadherin-6::EGFP-BAC transgenesis underscores the role of cadherins in hindbrain compartmentalization.
Neurosci. Res., 63, 2-9, 2009

Sone M, Uchida A, Komatsu A, Suzuki E, Ibuki I, Asada M, Shiwaku H, Tamura T, Hoshino M, OkazawaH, Nabeshima Y:
Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening.
PloS ONE, 4, e4466, 2009

Qin J, Xie Y, Wang B, Hoshino M, Wolff DW, Zhao J, Scofield MA, Dowd FJ, Lin M-F, Tu Y:
Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
Oncogene, 28, 1853-1863, 2009

Cao Y, Masuho I, Okawa H, Xie K, Asami J, Kammermeier PJ, Maddox DM, Furukawa T, Inoue T, Sampath AP, Martemyanov KA:
Retina specific GTPase accelerator RGS11/Gb5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons.
J. Neurosci. 29, 9301-9313, 2009

Ono K, Nakagawa T, Kojima K, Matsumoto M, Kawauchi T, Hoshino M, Ito J:
Silencing p27 reverses post-mitotic state of supporting cells in neonatal mouse cochleae.
Mol Cell Neurosci. 42, 391-398, 2009

Enomoto A, Asai N, Namba T, Wang Y, Kato T, Tanaka M, Tatsumi H, Taya S, Tsuboi D, Kuroda K, Kaneko N, Sawamoto K, Miyamoto R, Jijiwa M, Murakumo Y, Sokabe M, Seki T, Kaibuchi K, Takahashi M:
Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.
Neuron, 63, 774-787, 2009

Hikita T, Taya S, Fujino Y, Taneichi-Kuroda S, Ohta K, Tsuboi D, Shinoda T, Kuroda K, Funahashi Y, Uraguchi-Asaki J, Hashimoto R, Kaibuchi K:
Proteomic analysis reveals novel binding partners of dysbindin, a schizophrenia-related protein.
J. Neurochem., 110, 1567-1574, 2009

Hashimoto R, Ohi K, Okada T, Yasuda Y, Yamamori H, Hori H, Hikita T, Taya S, Saitoh O, Kosuga A, Tatsumi M, Kamijima K, Kaibuchi K, Takeda M, Kunugi H:
Association analysis between schizophrenia and the AP-3 complex genes.
Neurosci. Res., 65, 113-115, 2009

Arimura N, Kimura T, Nakamuta S, Taya S, Funahashi Y, Hattori A, Shimada A, Ménager C, Kawabata S, Fujii K, Iwamatsu A, Segal RA, Fukuda M, Kaibuchi K:
Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27.
Dev. Cell, 16, 675-686, 2009

Taneichi-Kuroda S, Taya S, Hikita T, Fujino Y, Kaibuchi K:
Direct interaction of Dysbindin with the AP-3 complex via its mu subunit.
Neurochem. Int., 54, 431-438, 2009

Inoue T, Inoue YU, Asami J, Izumi H, Nakamura S, Krumlauf R:
Analysis of mouse Cdh6 gene regulation by transgenesis of modified bacterial artificial chromosomes.
Dev Biol, 315, 506-520, 2008

Fukuda A, Kawaguchi Y, Furuyama F, Kodama S, Horiguchi M, Kuhara T, Kawaguchi M, Terao M, Doi R, Wright CVE, Hoshino M, Chiba T, Uemoto S:
Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes mellitus in mice.
Diabetes, 57, 2421-2431, 2008

Masuho I, Mototani Y, Sahara Y, Asami J, Nakamura S, Kozasa T, Inoue, T:
Dynamic expression patterns of G protein-regulated inducer of neurite outgrowth 1 (GRIN1) and its colocalization with Gao implicate significant roles of Gao-GRIN1 signaling in nervous system.
Dev. Dyn. 237, 2415-2429, 2008

Inoue YU, Asami J, Inoue T:
Cadherin-6 gene regulatory patterns in the postnatal mouse brain.
Mol. Cell. Neurosci., 39, 95-104, 2008.

Kumanogoh H, Asami J, Nakamura S, Inoue T:
Balanced expression of various TrkB receptor isoforms from the Ntrk2 gene locus in the mouse nervous system.
Mol Cell Neurosci. 39, 465-477, 2008

Tsuda R, Kumanogoh H, Umeda M, Maekawa S:
Morphological analysis on the distribution of membrane lipids and a membrane protein, NAP-22, during neuronal development in vitro.
J Mol Histol. 39, 371-379. 2008

Masutani T, Taguchi K, Kumanogoh H, Nakamura S, Maekawa S:
Molecular interaction of neurocalcin alpha with alsin (ALS2).
Neurosci. Lett. 438, 26-28, 2008

Maimaitiyiming M, Kumanogoh H,Nakamura S, Nagata K, Suzaki T, Maekawa S:
Biochemical characterization of membrane-associated septin from rat brain.
J Neurochem. 106, 1175-1183, 2008

Yamada M, Terao M, Terashima T, Fujiyama T, Kawaguchi Y, Nabeshima Y, Hoshino M:
Origin of climbing fiber neurons and their developmental dependence on Ptf1a.
J. Neurosci., 27, 10924-10934, 2007)
（同じ雑誌のJournal Clubでこの論文の解説がされました。J. Neurosci. 9, 338-339, 2008)

Takemoto-Kimura S, Ishihara-Ageta N, Nonaka M, Adachi-Morishima A, Mano T, Okamura M, Fujii H, Fuse T, Hoshino M, Suzuki S, Kojima M, Mishina M, Okuno H, Bito H:
Regulation of dendritogenesis via a lipid raft-associated Ca2+/calmodulin-dependent proteini kinase CLICK-III/CaMKIg.
Neuron, 54, 755-770, 2007

Shima Y, Kawaguchi SY, Kosaka K, Nakayama M, Hoshino M, Nabeshima Y, Hirano T, Uemura T:
Opposing roles in neurite growth control by two 7-pass transmembrane cadherins.
Nature Neuroscience, 10, 963-969, 2007

Jacobs T, Causeret F, Nishimura YV, Terao M, Norman A, Hoshino M, Nikolic M:
Localized activation of Pak1 controls neuronal polarity and morphology.
J. Neurosci., 27, 8604-8615, 2007
(Selected in “This week in the journal”)

Causeret F, Jacobs T, Terao M, Heath O, Hoshino M, Nikolic M:
Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migration.
Molecular Biol. Cell, 18, 4327-4342, 2007
（雑誌の表紙になりました ）

Zhao T, Nalbant P, Hoshino M, Dong X, Wu D, Bokoch GM:
Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function.
J. Leukocyte Biol., 81, 1127-1136, 2007

Takefuji M, Mori K, Morita Y, Arimura N, Nishimura T, Nakayama M, Hoshino M, Iwamatsu A, Murohara T, Kaibuchi K, Amano M:
Rho-kinase modulates the function of STEF, a Rac GEF, through its phosphorylation.
Biochem. Biophys. Res. Comm., 355, 788-794, 2007

ZalduaN , Gastineau M, Hoshino M, Lezoualc’h F, Zugaza JL:
Epac signaling pathway involves STEF a guanine nucleotide exchange factor for Rac to regulate APP processing.
FEBS Letter 581, 5814-5818, 2007

Kawauchi T, Chihama K, Nabeshima Y, Hoshino M:
Cdk5 phosphorylates and stabilizes p27kip1, contributing to actin organization and cortical neuronal migration.
Nature Cell Biol. 8, 17-26, 2006
（同じ号のNews & Viewsで紹介されました）

Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, Nishimura YV, Fukuda A, Fuse T, Matsuo N, Sone M, Watanabe M, Bito H, Terashima T, Wright CVE, Kawaguchi Y, Nakao K, Nabeshima Y:
Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum.
Neuron, 47, 201-213, 2005

Yoshizawa M, Kawauchi T, Sone M, Nishimura YV, Terao M, Chihama K, Nabeshima Y, Hoshino M:
Involvement of a Rac activator, P-Rex1, in neurotrophin-derived signaling and neuronal migration.
J. Neurosci. 25, 4406-4419, 2005

Kawauchi T, Chihama K, Nishimura YV, Nabeshima Y, Hoshino M:
MAP1B phosphorylation is differentially regulated by Cdk5/p35, Cdk5/p25 and JNK.
Biochem. Biophys. Res. Comm., 331, 50-55, 2005Dezawa M, Ishikawa H, Itokazu Y, Yoshihara T, Hoshino M, Takeda S, Ide C, Nabeshima Y:
Bone marrow stromal cells generate muscle cells and repair muscle degeneration.
Science, 309, 314-317 (2005)

Nishimura T, Yamaguchi T, Kato K, Yoshizawa M, Nabeshima Y, Ohno S, Hoshino M, Kaibuch K:
PAR-6-PAR-3 mediates Cdc42 signaling to Rac activation through STEF/Tiam1, RacGEFs.
Nature Cell Biol. 7, 270-277, 2005

Dezawa M, Kanno H, Hoshino M, Cho H, Matsumoto N, Itokazu Y, Tajima N, Yamada H, Sawada H, Ishikawa H, Mimura T, Kitada M, Suzuki Y, Ide C:
Specific induction of neuronal cells from bone-marrow stromal cells and application for autologous transplantation.
J. Clin. Invest., 113, 1701-1710, 2004

Kawauchi T, Chihama K, Nabeshima Y, Hoshino M:
The in vivo roles of STEF/Tiam1, Rac1 and JNK in cortical neuronal migration.
EMBO Journal, 22, 4190-4201, 2003

Yoshizawa M, Sone M, Matsuo N, Nagase T, Ohara O, Nabeshima Y, Hoshino M:
Dynamic and coordinated expression profiles of Dbl-family guanine nucleotide exchange factors in the developing mouse brain.
Gene Expression Patterns, 3, 375-381, 2003

Matsuo N, Terao M, Nabeshima Y, Hoshino M:
Roles of STEF/Tiam1, guanine necleotide exchange factors for Rac1, in regulation of growth cone morphology.
Mol. Cell. Neurosci., 24, 69-81, 2003
（雑誌の表紙になりました）

Yoshizawa M, *Hoshino M, Sone M, Nabeshima Y:
Expression of stef, an activator of Rac1, correlates with the stages of neuronal morphological development in the mouse brain.
Mech. Dev., 113, 65-68, 2002 (*corresponding author)

Matsuo M, *Hoshino M, Yoshizawa Y, Nabeshima Y:
Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth.
J. Biol. Chem. 277, 2860-2868, 2002 (*corresponding author)

Sone M, Suzuki E, Hoshino M, Hou D, Kuromi H, Fukata M, Kuroda S, Kaibuchi K, Nabeshima Y, Hama C:
Synaptic development is controlled in the periactive zones of Drosophila synapses.
Development,127, 4157-4168, 2000

Hoshino M, Sone M, Fukata M, Kuroda S, Kaibuchi K, Nabeshima Y, Hama C:
Identification of the stef gene that encodes a novel guanine-nucleotide exchange factor specific for Rac1.
J. Biol. Chem., 274, 17837-17844, 1999

Hoshino M, Suzuki E, Miyake T, Sone M, Komatsu A, Nabeshima Y, Hama C:
Neural expression of Hikaru genki protein during embryonic and larval development of Drosophila melanogaster
Dev. Genes Evol.,209, 1-9, 1999

Sone M, Hoshino M, Suzuki E, Kuroda S, Kaibuchi K, Nakagoshi H, Saigo K, Nabeshima Y, Hama C:
Still life, a protein in synaptic terminals of Drosophila homologous to GDP-GTP exchangers.
Science, 275, 543-547, 1997

Hoshino M, Suzuki E, Nabeshima Y, Hama C:
Hikaru genki protein is secreted into synaptic clefts from an early stage of synapse formation in Drosophila
Development, 122, 589-597, 1996

Hoshino M, Matsuzaki F, Nabeshima Y, Hama C:
hikaru genki, a CNS-specific gene identified by abnormal locomotion in Drosophila, encodes a novel type of protein.
Neuron, 10, 395-407, 1993

(English)

Hori K,Hoshino M:
Neuronal Migration and AUTS2 Syndrome.
Brain Sci. 2017 May 14;7(5):54. doi: 10.3390/brainsci70500542

Hori K,Hoshino M:
GABAergic neuron specification in the spinal cord, the cerebellum and the cochlear nucleus
Neural Plasticity, 2012:921732, 2012

Hoshino M:
Neuronal subtype specification in the cerebellum and dorsal hindbrain.
Dev Growth Differ, 54, 317-326, 2012

Hoshino M, Seto Y, Yamada M:
Specification of cerebellar and precerebellar neurons: HANDBOOK OF THE CEREBELLUM AND CEREBELLAR DISORDERS, Springer, 2012

Kawauchi T, Hoshino M:
Molecular pathways regulating cytoskeletal organization and morphological changes in migrating neurons
Developmental Neuroscience, 30, 36-46, 2008

Hoshino M:
Molecular machinery governing GABAergic neuron specification in the cerebellum.
The Cerebellum, 5, 193-198, 2006

Dezawa M, Hoshino M, Ide C:
Treatment of neurodegenerative diseases using adult bone marrow stromal cell-derived neurons.
Expert Opinion on Biological Therapy, 5, 427-435, 2005

Dezawa M, Hoshino M, Nabeshima Y, Ide C:
Marrow stromal cells: implications in health and disease in the nervous system.
Current Molecular Medicine, 5, 653-662, 2005

Dezawa M, Ishikawa H, Hoshino M, Itokazu Y, Nabeshima Y:
Potential of bone marrow stromal cell in application to neurodegenerative and muscle degenerative diseases.
Current Neuropharmacology 3, 257-266, 2005